SCHEMBL23827232

SCHEMBL23827232

COc1ccc(C(OC[C@@]23CN(C)[C@@H]([C@H](n4cnc5c(OC(=O)N(c6ccccc6)c6ccccc6)nc(NC(=O)C(C)C)nc54)O2)[C@@H]3O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CDK5 Q00535 4/20 0.37
CDK5R1 Q15078 4/20 0.37
TYMP P19971 4/20 0.36
ADORA2A P29274 5/20 0.33
ADORA3 P0DMS8 4/20 0.33
ADORA1 P30542 3/20 0.33
ADORA2B P29275 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30898740 0.93 CDK5 (0.36) CDK5CDK5R1TYMPADORA2AADORA3
SCHEMBL20394040 0.92 CDK5 (0.35) CDK5CDK5R1TYMPADORA2AADORA3
SCHEMBL20394011 0.88 TYMP (0.38) CDK5CDK5R1TYMPADORA2AADORA3
SCHEMBL23827313 0.87 CDK5 (0.35) CDK5CDK5R1TYMPADORA2AADORA3
SCHEMBL30898738 0.85 CDK5 (0.36) CDK5CDK5R1TYMPADORA2AADORA3
SCHEMBL20393990 0.85 CDK5 (0.36) CDK5CDK5R1TYMPADORA2AADORA3
SCHEMBL30002219 0.82 TYMP (0.56) TYMPADORA1
SCHEMBL24177249 0.82 TYMP (0.37) CDK5CDK5R1TYMPADORA2AADORA3
SCHEMBL23827243 0.82 CDK5 (0.30) CDK5CDK5R1
SCHEMBL23827202 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340584-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-11-06 US disclosed
CN-119119156-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-12-13 CN disclosed
CN-112996522-B Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-09-20 CN disclosed
CN-117964674-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
CN-117964673-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
EP-4275689-A2 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA Mitsubishi Tanabe Pharma Corporation (JP) 2023-11-15 EP disclosed
EP-3881851-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA Mitsubishi Tanabe Pharma Corporation (JP) 2021-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340584-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA POLN, DDX21, MUS81 CDK5 3819/4885CDK5R1 3629/4885TYMP 1322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.