Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401188 | 1.00 | TSHR (0.52) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL11579949 | 1.00 | TSHR (0.52) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL7352946 | 0.91 | LMNA (0.46) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL30945134 | 0.86 | LMNA (0.52) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL5729462 | 0.84 | — | — | |
| SCHEMBL17866310 | 0.81 | FFAR4 (0.55) | TSHRLMNANFKB1PMP22FFAR4 | |
| SCHEMBL11705517 | 0.81 | FFAR4 (0.55) | TSHRLMNANFKB1PMP22FFAR4 | |
| SCHEMBL11503082 | 0.79 | FFAR4 (0.69) | TSHRLMNAFFAR4FFAR1ALDH1A1 | |
| SCHEMBL11046849 | 0.79 | TSHR (0.48) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL23829588 | 0.79 | FFAR4 (0.69) | TSHRLMNAFFAR4FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |