Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE6D | O43924 | 5/20 | 0.67 |
| ▸ | PDE6A | P16499 | 5/20 | 0.67 |
| ▸ | PDE6G | P18545 | 5/20 | 0.67 |
| ▸ | PDE6B | P35913 | 5/20 | 0.67 |
| ▸ | PDE6C | P51160 | 5/20 | 0.67 |
| ▸ | PDE6H | Q13956 | 5/20 | 0.67 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | IL1B | P01584 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23830375 | 0.94 | PDE6D (0.75) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830285 | 0.92 | PDE6D (0.65) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830282 | 0.87 | PDE6D (0.60) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830281 | 0.86 | PDE6D (0.75) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830395 | 0.85 | PDE6D (0.47) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830321 | 0.85 | PDE6D (0.47) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830423 | 0.84 | PDE6D (0.46) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL16406000 | 0.84 | PDE6D (0.86) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL23830288 | 0.81 | PDE6D (0.51) | PDE6DPDE6APDE6GPDE6BPDE6C | |
| SCHEMBL16395561 | 0.80 | PDE6D (1.00) | PDE6DPDE6APDE6GPDE6BPDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | CADILA HEALTHCARE LIMITED (IN) | 2021-09-23 | — | — | US | claimed |
| CN-112543757-A | Condensed azaheteroaryl compounds having antibacterial activity against tubercle bacillus | 卡迪拉保健有限公司 | 2021-03-23 | — | — | CN | claimed |
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | CADILA HEALTHCARE LIMITED (IN) | 2021-09-23 | — | — | US | disclosed |
| CN-112543757-A | Condensed azaheteroaryl compounds having antibacterial activity against tubercle bacillus | 卡迪拉保健有限公司 | 2021-03-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292333-A1 | CONDENSED AZAHETEROARYL COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY AGAINST TUBERCULOSIS BACTERIA | DPEP1, SAT1, PEPD | PDE6D 3804/4885PDE6A 1704/4885PDE6G 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.