DPEP1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL13240770	1.00	10/20
SCHEMBL13240771	1.00	10/20
SCHEMBL13240773	1.00	10/20
SCHEMBL13240775	1.00	10/20
SCHEMBL13240776	1.00	10/20
SCHEMBL13241006	1.00	10/20
SCHEMBL13241007	1.00	10/20
SCHEMBL13241008	1.00	10/20
SCHEMBL13241009	1.00	10/20
SCHEMBL13241012	1.00	10/20
SCHEMBL13241013	1.00	10/20
SCHEMBL13240772	0.74	10/20
SCHEMBL13240774	0.74	10/20
SCHEMBL9645166	0.63	10/20
SCHEMBL9646018	0.63	10/20
SCHEMBL9646942	0.63	10/20
SCHEMBL9647109	0.63	10/20
SCHEMBL9647128	0.63	10/20
SCHEMBL9647139	0.63	10/20
SCHEMBL9645188	0.56	10/20

Clinical trials — most relevant to DPEP1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Identification of Polymorphisms Involved in the Metabolism of Propofol	PHASE4	COMPLETED
Peptide Vaccine Focusing on Prevention of the Recurrence for Bladder Cancer	PHASE2	UNKNOWN
Pharmacogenetics of Disulfiram for Cocaine	PHASE2	COMPLETED
Novel Peptide Vaccination for Patients With Advanced Bladder Cancer	PHASE1	COMPLETED
The Enzymatic Activity of Lymphocyte Dihydropyrimidine Dehydrogenase DPD in the Blood as a Predictive and Prognostic Factor in Patients With Digestive Cancer in the First or Second Metastatic Line	nan	UNKNOWN
Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)	nan	RECRUITING
PCD New Gene Discovery	nan	COMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED
Genetic Studies of Lysosomal Storage Disorders	nan	ENROLLING_BY_INVITATION
Genetic Variants and Regulation of Specialized Pro-resolving Mediator	nan	RECRUITING
A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders	nan	RECRUITING
Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3	nan	COMPLETED
Identification of an Asthma Susceptibility Gene on 3P	nan	COMPLETED
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study	nan	COMPLETED
Improving the Safety of Fluoropyrimidine-based Chemotherapy	nan	UNKNOWN
Genetic DAO Deficiency and Lower Urinary Tract Symptoms	nan	COMPLETED
Genetic Epidemiology of Asthma in Costa Rica	nan	COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
In Vivo Assessment of Histamine Pharmacodynamics	nan	WITHDRAWN
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
A Study of the Genetic Analysis of Brain Disorders	nan	COMPLETED
Sodium Transport: Genetics and Hypertension	nan	COMPLETED
Genetics of Prostate Cancer in Young Patients	nan	COMPLETED
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations	nan	COMPLETED
Relationship Between Genes Important in Blood Pressure Regulation and Blood Pressure Therapy in Hypertension	nan	COMPLETED
Biomarker for Hypophosphatasia Disease (BioHypophos)	nan	WITHDRAWN
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte	nan	COMPLETED
Pharmacogenetic and Neurofunctional Brain Areas Study in Obese Patients With Binge Eating Disorder	nan	UNKNOWN
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans	nan	UNKNOWN
Gait in Rare Diseases	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a DPEP1 binder may also engage these)

Protein	Name	Similarity
P31428	—	1.000	P31428 →
P22412	—	1.000	P22412 →
Q3SZM7	—	1.000	Q3SZM7 →
P31429	—	1.000	P31429 →
P43477	—	0.997	P43477 →
P31430	—	0.993	P31430 →
Q5M872	—	0.987	Q5M872 →
Q8C255	—	0.986	Q8C255 →
D4DEJ7	—	0.984	D4DEJ7 →
Q6Q886	—	0.983	Q6Q886 →
Q58DH9	—	0.982	Q58DH9 →
Q9QWR8	—	0.982	Q9QWR8 →
Q2KIM0	—	0.982	Q2KIM0 →
P17164	—	0.982	P17164 →
Q2UPB0	—	0.982	Q2UPB0 →
Q99LJ1	—	0.982	Q99LJ1 →
P70699	—	0.981	P70699 →
GAA	Lysosomal alpha-glucosidase	0.981	landscape →
GLA	Alpha-galactosidase A	0.981	landscape →
P51569	—	0.981	P51569 →
M1VV65	—	0.981	M1VV65 →
C5FK77	—	0.980	C5FK77 →
E5R2Q7	—	0.980	E5R2Q7 →
Q28193	—	0.980	Q28193 →
P58780	—	0.980	P58780 →
Q9DA79	—	0.980	Q9DA79 →
Q2VQV9	—	0.980	Q2VQV9 →
C7ZIE1	—	0.980	C7ZIE1 →
Q9H4A9	—	0.980	Q9H4A9 →
Q7M758	—	0.979	Q7M758 →