Malonic Acid

Malonic Acid

SCHEMBL23831

O=C(O)CC(=O)O.O=C(O)CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 1.00
SRR Q9GZT4 1/20 1.00
LMNA P02545 3/20 0.50
EGLN1 Q9GZT9 2/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
SUCNR1 Q9BXA5 1/20 0.50
TSHR P16473 4/20 0.46
FFAR3 O14843 2/20 0.46
GLRA1 P23415 1/20 0.46
SLC6A9 P48067 1/20 0.46
OR51E2 Q9H255 1/20 0.46
SLC22A6 Q4U2R8 2/20 0.43
KDM4E B2RXH2 2/20 0.42
CYP2D6 P10635 3/20 0.40
ALOX15 P16050 2/20 0.40
CYP2C19 P33261 1/20 0.40
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL28221810 1.00 LDHA (1.00) LDHASRRLMNAEGLN1ALKBH5
Malonic Acid SCHEMBL1332554 1.00
Malonic Acid SCHEMBL336 1.00
Malonic Acid SCHEMBL1332405 1.00
Malonic Acid SCHEMBL3358611 1.00
Malonic Acid SCHEMBL1332587 1.00
Malonic Acid SCHEMBL1698280 0.95
Malonic Acid SCHEMBL21878523 0.95
Malonic Acid SCHEMBL5179779 0.95
Malonic Acid SCHEMBL22409621 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111563-A1 MILK PEPTIDE COMPOSITIONS FOR PHARMACEUTICAL AND COSMECEUTICAL USE MATRUBIALS INC. (US) 2025-05-30 WO claimed
CN-104245728-A Method for enriching IGA CSL BEHRING AG 2014-12-24 CN claimed
CN-103687959-A Methods, compositions and kits for assaying mitochondrial function BAYSTATE MEDICAL CT INC 2014-03-26 CN claimed
US-8105492-B2 Methods for recharging nanoparticle-treated beds BAKER HUGHES INCORPORATED (US) 2012-01-31 US claimed
WO-2011003116-A2 BETA-AMINO ACID COMPRISING ELECTROLYTE AND METHOD FOR THE DEPOSITION OF A METAL LAYER ENTHONE INC. (US) 2011-01-06 WO claimed
EP-2270255-A1 Beta-amino acid comprising electrolyte and method for the deposition of a metal layer Enthone, Inc. (US) 2011-01-05 EP claimed
EP-4727448-A1 OPTICAL CHEMICAL SENSOR SYSTEM WITH MICRONEEDLES Cardiac Pacemakers, Inc. (US) 2026-04-22 EP disclosed
US-20250340592-A1 MAMMALIAN MILK-DERIVED PEPTIDES WITH ANTIMICROBIAL ACTIVITY MATRUBIALS INC (US) 2025-11-06 US disclosed
CN-120064503-A Metabolic biomarker combinations for depression diagnosis 南京利康医药科技有限公司 2025-05-30 CN disclosed
WO-2025111563-A1 MILK PEPTIDE COMPOSITIONS FOR PHARMACEUTICAL AND COSMECEUTICAL USE MATRUBIALS INC. (US) 2025-05-30 WO disclosed
EP-4559902-A2 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE Imago Biosciences Inc. (US) 2025-05-28 EP disclosed
CN-119224186-B Metabolic biomarker combinations for depression diagnosis 南京利康医药科技有限公司 2025-04-11 CN disclosed
CN-119709450-A Recombinant host cells for malonate production 利戈斯股份有限公司 2025-03-28 CN disclosed
CN-100415126-C Method for extracting tobacco essence perfume GUANGQUAN SONG (CN) 2008-09-03 CN disclosed
WO-2007038524-A2 COCRYSTALLIZATION METHODS SSCI, INC. (US) 2007-04-05 WO disclosed
CN-1899141-A Method for extracting tobacco essence perfume SONG GUANGQUAN (CN) 2007-01-24 CN disclosed
CN-1351851-A Continuously producing process for general artificial tobacco leaf SONG ZHENZHONG (CN) 2002-06-05 CN disclosed
CN-1054148-C Polyurethane sealant compositions ESSEX SPECIAL PRODUCTS INC (US) 2000-07-05 CN disclosed
CN-1077212-A Composition of the ester of carboxy-containing copolymer and using method thereof LUBRIZOL CORP (US) 1993-10-13 CN disclosed
US-4912114-A Containing an ether in position 3 and amine in position 4 SANDOZ LTD. (CH) 1990-03-27 US disclosed