Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105281 | 0.92 | TRPV1 (0.57) | TRPV1KDRUBE2MDCUN1D1RXFP1 | |
| SCHEMBL23831879 | 0.92 | TRPV1 (0.57) | TRPV1KDRUBE2MDCUN1D1RXFP1 | |
| SCHEMBL30105040 | 0.89 | TRPV1 (0.52) | TRPV1KDRUBE2MDCUN1D1RXFP1 | |
| SCHEMBL23831649 | 0.89 | TRPV1 (0.52) | TRPV1KDRUBE2MDCUN1D1RXFP1 | |
| SCHEMBL23831577 | 0.86 | MEN1 (0.58) | TRPV1KDRLMNASMN1; SMN2POLB | |
| SCHEMBL30105077 | 0.86 | MEN1 (0.58) | TRPV1KDRLMNASMN1; SMN2POLB | |
| SCHEMBL23831741 | 0.84 | TRPV1 (0.59) | TRPV1KDRUBE2MDCUN1D1RXFP1 | |
| SCHEMBL30105296 | 0.83 | TRPV1 (0.52) | TRPV1UBE2MDCUN1D1MEN1MAPT | |
| SCHEMBL23831639 | 0.83 | TRPV1 (0.52) | TRPV1UBE2MDCUN1D1MEN1MAPT | |
| SCHEMBL23831708 | 0.82 | TRPV1 (0.59) | TRPV1KDRLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021185391-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2021-09-23 | — | — | WO | disclosed |