Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831577 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL23831806 | 0.91 | MEN1 (0.61) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL30104927 | 0.91 | MEN1 (0.61) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL23832007 | 0.89 | MEN1 (0.59) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL30105261 | 0.89 | MEN1 (0.59) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL23831782 | 0.86 | TRPV1 (0.57) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL30104979 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL23831916 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL23831708 | 0.82 | TRPV1 (0.59) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL23832019 | 0.82 | TRPV1 (0.56) | MEN1KMT2AMAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |