SCHEMBL23833797

SCHEMBL23833797

CC(C)(C)OC(=O)NC1(C(=O)O)CC(O)C(F)C1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
BTK Q06187 1/20 0.33
DPP8 Q6V1X1 3/20 0.32
DPP9 Q86TI2 3/20 0.32
APLNR P35414 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
EPHX2 P34913 1/20 0.30
CACNA1H O95180 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22362933 0.84 MEN1 (0.41) MEN1MAPK1KMT2ABTKDPP8
SCHEMBL31527127 0.83 MEN1 (0.42) MEN1MAPK1KMT2ABTKNFKB1
SCHEMBL25492182 0.82 MEN1 (0.34) MEN1MAPK1KMT2ADPP8DPP9
SCHEMBL25492269 0.82 MEN1 (0.34) MEN1MAPK1KMT2ADPP8DPP9
SCHEMBL23833804 0.82 MEN1 (0.34) MEN1MAPK1KMT2ADPP8DPP9
SCHEMBL25492257 0.82 MEN1 (0.34) MEN1MAPK1KMT2ADPP8DPP9
SCHEMBL23833802 0.79 MEN1 (0.33) MEN1MAPK1KMT2A
SCHEMBL23833789 0.79 MEN1 (0.33) MEN1MAPK1KMT2A
SCHEMBL23833800 0.79 MEN1 (0.33) MEN1MAPK1KMT2A
SCHEMBL23833798 0.79 MEN1 (0.33) MEN1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158178-A1 Radionuclide Tracers of 1-Amino-3,4-Difluorocyclopentane-1-Carboxylic Acid, Derivatives, and Uses Thereof UNIV EMORY (US) 2023-05-25 US disclosed
EP-4121121-A1 RADIONUCLIDE TRACERS OF 1-AMINO-3,4-DIFLUOROCYCLOPENTANE-1-CARBOXYLIC ACID, DERIVATIVES, AND USES THEREOF Emory University (US) 2023-01-25 EP disclosed
WO-2021188592-A1 RADIONUCLIDE TRACERS OF 1-AMINO-3,4-DIFLUOROCYCLOPENTANE-1-CARBOXYLIC ACID, DERIVATIVES, AND USES THEREOF EMORY UNIVERSITY (US) 2021-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158178-A1 Radionuclide Tracers of 1-Amino-3,4-Difluorocyclopentane-1-Carboxylic Acid, Derivatives, and Uses Thereof AFF1, METTL3, VHL MEN1 790/4885MAPK1 3027/4885KMT2A 703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.