⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601768 | 1.00 | — | — | |
| SCHEMBL3626522 | 1.00 | — | — | |
| SCHEMBL29728566 | 0.81 | TSHR (0.60) | — | |
| SCHEMBL4009243 | 0.80 | — | — | |
| SCHEMBL28384882 | 0.80 | — | — | |
| SCHEMBL23725742 | 0.79 | — | — | |
| SCHEMBL473155 | 0.79 | — | — | |
| SCHEMBL3504870 | 0.79 | — | — | |
| SCHEMBL225530 | 0.79 | TSHR (0.58) | — | |
| SCHEMBL25200468 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476876-B1 | PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2023-08-09 | — | — | EP | claimed |
| CN-112708321-A | Modified acrylic resin finish paint for railway building materials and preparation method thereof | 山东齐鲁漆业有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-110637015-A | Farnesoin X receptor agonists and uses thereof | 梅塔科林公司 | 2019-12-31 | — | — | CN | claimed |
| EP-0012587-B1 | THERMO-SENSITIVE MULTI-COLOR RECORDING MATERIAL AND PROCESS FOR PREPARATION THEREOF | Ricoh Company, Ltd (JP) | 1983-05-25 | — | — | EP | claimed |
| US-4078146-A | TREATMENT OF CARDIO-VASCULAR DISORDERS | AKTIEBOLAGET HASSLE (SW) | 1978-03-07 | — | — | US | claimed |
| CN-118239948-A | Solid forms and methods of making fused tricyclic compounds, including methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118019750-A | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-115785074-B | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117946107-A | Solid forms and methods of making fused tricyclic compounds, including methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117946098-A | Pyrimidine PLK1 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117897146-A | Novel process for synthesizing enantiomerically pure (S) -methadone, (R) -methadone, racemic (R, S) -methadone and related analogues | 保罗·L·曼佛雷蒂 | 2024-04-16 | — | — | CN | disclosed |
| EP-4349828-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Yingli Pharmaceutical Co. Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |
| EP-1268410-A1 | BETA-HYDROXY BUTENYL CARBAMATE, FUNCTIONAL OLIGOMERS AND COATINGS THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6465679-B2 | (VINYL)-2-HYDROXYETHYL CARBAMATE; OLIGOMERS WITH A POLYISOCYANATE; CURABLE COATING COMPOSITIONS WITH MELAMINE-FORMALDEHYDE RESIN; LOW SOLUTION VISCOSITY, FOR USE IN HIGH SOLIDS COATINGS | EASTMAN CHEMICAL COMPANY | 2002-10-15 | — | — | US | disclosed |
| US-20020040110-A1 | Carbamate functional oligomers and coatings therefrom | EASTMAN CHEMICAL COMPANY | 2002-04-04 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001049658-A1 | BETA-HYDROXY BUTENYL CARBAMATE, FUNCTIONAL OLIGOMERS AND COATINGS THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2001-07-12 | — | — | WO | disclosed |
| US-5912382-A | CARBAMYLATION BY REACTION OF AMINE WITH ALKYLENE CARBONATE IN THE PRESENCE CATALYST | HUNTSMAN PERTOCHEMICAL CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| WO-1998011112-A1 | TRICYCLIC INDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SYNTHELABO (FR) | 1998-03-19 | — | — | WO | disclosed |
| US-5115070-A | Also containing biuret, thiourea, dithiobiuret, amide and thioamide group with polyether and hydroxyalkylcarbamates for flexible polyurethane foams, plastics and surfactants | THE DOW CHEMICAL COMPANY (US) | 1992-05-19 | — | — | US | disclosed |