⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626522 | 1.00 | — | — | |
| SCHEMBL2383537 | 1.00 | — | — | |
| SCHEMBL29728566 | 0.81 | TSHR (0.60) | — | |
| SCHEMBL4009243 | 0.80 | — | — | |
| SCHEMBL28384882 | 0.80 | — | — | |
| SCHEMBL23725742 | 0.79 | — | — | |
| SCHEMBL473155 | 0.79 | — | — | |
| SCHEMBL3504870 | 0.79 | — | — | |
| SCHEMBL225530 | 0.79 | TSHR (0.58) | — | |
| SCHEMBL25200468 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110637015-A | Farnesoin X receptor agonists and uses thereof | 梅塔科林公司 | 2019-12-31 | — | — | CN | claimed |
| EP-1266900-A1 | Carbamates of rapamycin | Wyeth (US) | 2002-12-18 | — | — | EP | claimed |
| EP-0593227-A1 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-20 | — | — | EP | claimed |
| US-5302584-A | Immunosuppressants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-12 | — | — | US | claimed |
| CN-118239948-A | Solid forms and methods of making fused tricyclic compounds, including methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-117946107-A | Solid forms and methods of making fused tricyclic compounds, including methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117897146-A | Novel process for synthesizing enantiomerically pure (S) -methadone, (R) -methadone, racemic (R, S) -methadone and related analogues | 保罗·L·曼佛雷蒂 | 2024-04-16 | — | — | CN | disclosed |
| EP-4349828-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Yingli Pharmaceutical Co. Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |
| US-20230391785-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, METHOD FOR PREPARING SAME AND USE OF SAME | 280 BIO, INC. (US) | 2023-12-07 | — | — | US | disclosed |
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116724038-A | Bicyclic compounds | 安力高医药股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116514813-A | Preparation method of tyrosine kinase inhibitor and intermediate thereof | 轩竹生物科技股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-101801939-A | Be used to strengthen the 3-replacement 1,2 of glutamatergic synaptic responses, 3-triazine-4-ketone and 3-replace 1, the 3-Pyrimdinone | CORTEX PHARMA INC | 2010-08-11 | — | — | CN | disclosed |
| CN-101641093-A | Imidazotriazines and imidazopyrimidines as kinase inhibitors | INCYTE CORP US | 2010-02-03 | — | — | CN | disclosed |
| WO-2009080676-A1 | NEW CALB MUTEINS AND THEIR USE | BASF SE (DE) | 2009-07-02 | — | — | WO | disclosed |
| CN-101212903-A | Polycyclic carbamoylpyridone derivatives having HIV integrase inhibitory activity | SMITHKLINE BEECHAM CORP (US) | 2008-07-02 | — | — | CN | disclosed |
| EP-1266900-A1 | Carbamates of rapamycin | Wyeth (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5411967-A | Antiinflammatory, immunosuppressant, antitumor | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0593227-A1 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5302584-A | Immunosuppressants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |