Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18489402 | 0.78 | FDFT1 (0.37) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL1241173 | 0.78 | FDFT1 (0.37) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL29480695 | 0.78 | FDFT1 (0.37) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL30467058 | 0.76 | LMNA (0.40) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL31201731 | 0.76 | LMNA (0.40) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL17154815 | 0.76 | LMNA (0.40) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL3603122 | 0.76 | UGT2B7 (0.38) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL17154813 | 0.76 | LMNA (0.40) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL961068 | 0.76 | LMNA (0.40) | UGT2B7OGAALDH1A1NOS3NOS1 | |
| SCHEMBL594060 | 0.74 | CYP3A4 (0.42) | UGT2B7ALDH1A1SMN1; SMN2POLBADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731963-B2 | Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]-methyl]-2,4-thiazolidinedione and salts thereof | MINORYX THERAPEUTICS S.L. (ES) | 2023-08-22 | — | — | US | disclosed |
| US-20220204496-A1 | PROCESS FOR PREPARING 5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY]PHENYL]-METHYL]-2,4-THIAZOLIDINEDIONE AND SALTS THEREOF | MINORYX THERAPEUTICS S.L. (ES) | 2022-06-30 | — | — | US | disclosed |
| US-11124505-B2 | Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione and salts thereof | MINORYX THERAPEUTICS S.L. (ES) | 2021-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204496-A1 | PROCESS FOR PREPARING 5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY]PHENYL]-METHYL]-2,4-THIAZOLIDINEDIONE AND SALTS THEREOF | CYP3A5, CYP3A4, UGT1A4 | UGT2B7 6/4885OGA 2920/4885ALDH1A1 133/4885 |
| US-11124505-B2 | Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione and salts thereof | CYP3A5, UGT1A4, CYP4B1 | UGT2B7 6/4885OGA 2549/4885ALDH1A1 134/4885 |
| US-11731963-B2 | Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]-methyl]-2,4-thiazolidinedione and salts thereof | CYP3A5, CYP3A4, UGT1A4 | UGT2B7 6/4885OGA 2920/4885ALDH1A1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.