Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18431341 | 0.87 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2SPHK1GAA | |
| SCHEMBL23837193 | 0.87 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2SPHK1GAA | |
| SCHEMBL16410506 | 0.87 | PTPN1 (0.51) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL29167418 | 0.85 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2SPHK1ATM | |
| SCHEMBL24427130 | 0.84 | MAPT (0.56) | NPC1RAB9ASMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL20580635 | 0.84 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2ATMGAA | |
| SCHEMBL23933133 | 0.84 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2ATMGAA | |
| SCHEMBL11808323 | 0.83 | MAPT (0.56) | NPC1RAB9ASMN1; SMN2ATMGAA | |
| SCHEMBL23071786 | 0.82 | SMN1; SMN2 (0.39) | NPC1RAB9ASMN1; SMN2SPHK1HDAC3 | |
| SCHEMBL22546078 | 0.82 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2SPHK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882349-A1 | (ANTI-CDH6 ANTIBODY)-(PYRROLOBENZODIAZEPINE DERIVATIVE) CONJUGATE | Daiichi Sankyo Company, Limited (JP) | 2021-09-22 | — | — | EP | disclosed |