SCHEMBL23837253

SCHEMBL23837253

CCOC(=O)n1nc(NC(=O)C2(S(C)(C)C)CCC2)c2c1C(C)(C)N(C(=O)OC(C)(C)C)C2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17724547 0.87 C5AR1 (0.31) C5AR1
SCHEMBL3331339 0.85 C5AR1 (0.34) C5AR1
SCHEMBL23837255 0.83 C5AR1 (0.33) C5AR1
SCHEMBL19312086 0.82 C5AR1 (0.35) C5AR1
SCHEMBL3458185 0.81 RAB9A (0.37) C5AR1
SCHEMBL19305433 0.81 C5AR1 (0.33) C5AR1
SCHEMBL24272891 0.80 C5AR1 (0.32) C5AR1
SCHEMBL17724526 0.80 C5AR1 (0.32) C5AR1
SCHEMBL19537513 0.79
SCHEMBL16622327 0.78 C5AR1 (0.37) C5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3214086-B1 SUBSTITUTED DIHYDROPYRROLOPYRAZOLE COMPOUND UBE INDUSTRIES (JP) 2021-09-22 EP disclosed