Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23837562 | 0.80 | CYP1A2 (0.45) | MTNR1AMTNR1BMAPTCYP1A2CYP2C9 | |
| SCHEMBL23837445 | 0.78 | AAK1 (0.31) | — | |
| SCHEMBL23837515 | 0.75 | MTNR1A (0.37) | MTNR1AMTNR1BMAPTCYP1A2CYP2C9 | |
| SCHEMBL23837471 | 0.73 | KCNA3 (0.32) | MTNR1AMTNR1B | |
| SCHEMBL23837525 | 0.71 | — | — | |
| SCHEMBL17337233 | 0.71 | PARP1 (0.32) | MTNR1AMTNR1BMAPT | |
| SCHEMBL17337236 | 0.71 | PARP1 (0.32) | MTNR1AMTNR1BMAPT | |
| SCHEMBL23130305 | 0.70 | HDAC3 (0.33) | MTNR1AMTNR1BMAPT | |
| SCHEMBL23129993 | 0.70 | — | — | |
| SCHEMBL23837563 | 0.70 | MTNR1A (0.37) | MTNR1AMTNR1BMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882252-A1 | BETA-LACTAMASE INHIBITORS | Venatorx Pharmaceuticals, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |