Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.78 |
| ▸ | LMNA | P02545 | 8/20 | 0.78 |
| ▸ | GAA | P10253 | 6/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | APAF1 | O14727 | 5/20 | 0.78 |
| ▸ | POLB | P06746 | 4/20 | 0.78 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.78 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.78 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.67 |
| ▸ | NSD2 | O96028 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MPI | P34949 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745582 | 0.88 | MAPT (1.00) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL11961914 | 0.88 | MAPT (1.00) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL1444105 | 0.88 | MAPT (1.00) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL11981855 | 0.82 | MAPT (0.82) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL1443113 | 0.82 | MAPT (0.82) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL11900788 | 0.81 | MAPT (1.00) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL11981638 | 0.81 | MAPT (1.00) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL11981834 | 0.80 | MEN1 (1.00) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL1444473 | 0.80 | MEN1 (1.00) | MAPTKDM4ELMNAGAAKMT2A | |
| SCHEMBL12819453 | 0.78 | GAA (0.80) | MAPTKDM4ELMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473486-B2 | PYRIMIDINES AS HEPCIDINE ANTAGONISTS | VIFOR INT AG (CH) | 2021-09-22 | — | — | EP | disclosed |