Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309707 | 0.84 | — | — | |
| SCHEMBL921779 | 0.84 | — | — | |
| SCHEMBL21524653 | 0.82 | PHGDH (0.30) | — | |
| SCHEMBL12424485 | 0.82 | PHGDH (0.30) | — | |
| SCHEMBL330457 | 0.82 | — | — | |
| SCHEMBL18571428 | 0.78 | CYP1A2 (0.41) | CYP1A2SIGMAR1 | |
| SCHEMBL23952730 | 0.78 | ACHE (0.45) | CYP1A2ACHESIGMAR1 | |
| SCHEMBL23952727 | 0.75 | ACHE (0.46) | CYP1A2ACHESIGMAR1 | |
| SCHEMBL23543239 | 0.75 | CYP1A2 (0.42) | CYP1A2SIGMAR1 | |
| SCHEMBL18638778 | 0.73 | CYP1A2 (0.36) | CYP1A2ACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057610-B1 | DRUG-CONJUGATES WITH A TARGETING MOLECULE AND TWO DIFFERENT DRUGS | SORRENTO THERAPEUTICS INC (US) | 2021-09-22 | — | — | EP | disclosed |