SCHEMBL23839903

SCHEMBL23839903

CC(C)CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C(NC(=O)C(CC1CCCCC1)NC(=O)C(N)CC(=O)O)c1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CO)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30802584 0.96 KISS1R (0.63) KISS1R
SCHEMBL29595208 0.93 KISS1R (0.62) KISS1R
SCHEMBL29595776 0.93 KISS1R (0.62) KISS1R
SCHEMBL19498884 0.89 KISS1R (0.62) KISS1R
SCHEMBL30675548 0.88 KISS1R (0.64) KISS1R
SCHEMBL30450426 0.88 KISS1R (0.63) KISS1R
SCHEMBL22822372 0.87 IL23R (0.60) KISS1R
SCHEMBL23346292 0.87 KISS1R (0.57) KISS1R
SCHEMBL15354488 0.86 IL23R (0.65) KISS1R
SCHEMBL29738146 0.86 KISS1R (0.75) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210290787-A1 MACROCYCLE CONJUGATES LUMIPHORE, INC. 2021-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210290787-A1 MACROCYCLE CONJUGATES FOLH1, KLK3, CD47 KISS1R 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback