Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.41 |
| ▸ | BMI1 | P35226 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24179379 | 0.93 | TSHR (0.54) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL24179327 | 0.90 | TSHR (0.54) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL13080878 | 0.83 | TSHR (0.73) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL24179293 | 0.81 | TSHR (0.45) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL19486460 | 0.81 | TSHR (0.82) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL15631604 | 0.81 | TSHR (0.71) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL3062634 | 0.80 | TSHR (0.70) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL16739793 | 0.78 | MAPK1 (0.53) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL20041714 | 0.78 | TSHR (0.58) | TSHRMAPK1HTTPIK3CDPIK3CA | |
| SCHEMBL13052907 | 0.78 | HTT (0.61) | TSHRMAPK1HTTPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-18 | — | — | US | disclosed |
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-18 | — | — | US | disclosed |
| WO-2021185712-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230157170-A1 | HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, CTCF, EED | TSHR 4785/4885MAPK1 3866/4885HTT 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.