Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 2/20 | 0.44 |
| ▸ | ALPP | P05187 | 1/20 | 0.44 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631604 | 0.84 | TSHR (0.71) | TSHRNPC1LMNARAB9AMAPK1 | |
| SCHEMBL20041464 | 0.84 | TSHR (0.70) | TSHRLMNAMAPK1HTTALDH1A1 | |
| SCHEMBL20041515 | 0.82 | TSHR (0.50) | TSHRNPC1LMNARAB9AMAPK1 | |
| SCHEMBL13080878 | 0.80 | TSHR (0.73) | TSHRNPC1LMNARAB9AMAPK1 | |
| SCHEMBL17570830 | 0.79 | TSHR (0.55) | TSHRNPC1RAB9AMAPK1HTT | |
| SCHEMBL19486460 | 0.78 | TSHR (0.82) | TSHRNPC1LMNARAB9AMAPK1 | |
| SCHEMBL23840294 | 0.78 | TSHR (0.61) | TSHRNPC1LMNARAB9AMAPK1 | |
| SCHEMBL29845601 | 0.76 | KCNMA1 (0.67) | TSHRNPC1LMNARAB9AMAPK1 | |
| SCHEMBL19486091 | 0.76 | TSHR (0.67) | TSHRLMNAMAPK1HTTALDH1A1 | |
| SCHEMBL890612 | 0.76 | KCNMA1 (0.67) | TSHRNPC1LMNARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |