Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833429 | 0.91 | HTR2C (0.43) | PIK3C3RXFP1POLBMAPTKDM4E | |
| SCHEMBL30151060 | 0.91 | HTR2C (0.43) | PIK3C3RXFP1POLBMAPTKDM4E | |
| SCHEMBL23840486 | 0.88 | IDH1 (0.40) | PIK3C3PIK3CAPOLBMAPTIDH1 | |
| SCHEMBL23840519 | 0.84 | MAP2K1 (0.42) | PIK3C3POLBMAPTIDH1ALPL | |
| SCHEMBL23840521 | 0.80 | IDH1 (0.37) | PIK3C3PIK3CAMTORPOLBIDH1 | |
| SCHEMBL30150995 | 0.78 | MAPT (0.46) | POLBMAPTIDH1KDM4EALDH1A1 | |
| SCHEMBL23833490 | 0.78 | MAPT (0.46) | POLBMAPTIDH1KDM4EALDH1A1 | |
| SCHEMBL23840394 | 0.78 | CCR4 (0.38) | PIK3C3PIK3CAMTORPOLBMAPT | |
| SCHEMBL25754534 | 0.78 | MEN1 (0.49) | RXFP1POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL23840579 | 0.77 | PIK3C3 (0.42) | PIK3C3PIK3CAMTORALPLBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188907-A1 | PYRIDINESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |