SCHEMBL238408

SCHEMBL238408

CCC(N)c1ccc(N)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.59
MAPT P10636 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 5/20 0.39
ALDH1A1 P00352 5/20 0.39
CYP3A4 P08684 4/20 0.39
TSHR P16473 3/20 0.39
GFER P55789 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
PSMD14 O00487 1/20 0.39
MAPK1 P28482 1/20 0.39
RECQL P46063 1/20 0.39
ACHE P22303 1/20 0.38
GAA P10253 2/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP19A1 P11511 1/20 0.35
ALOX15 P16050 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1187344 0.98 SLC6A4 (0.57) SLC6A4MAPTMEN1KMT2ATDP1
SCHEMBL23092069 0.89 SLC6A4 (0.70) SLC6A4MAPTTDP1ALDH1A1CYP3A4
SCHEMBL8284225 0.85 SLC6A4 (0.59) SLC6A4MAPTTDP1ALDH1A1CYP3A4
SCHEMBL8285910 0.85 SLC6A4 (0.59) SLC6A4MAPTTDP1ALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL4935308 0.83 SLC6A4 (0.57) SLC6A4TDP1ALDH1A1L3MBTL1MAPK1
Hydrochloric Acid SCHEMBL4938618 0.83 SLC6A4 (0.57) SLC6A4TDP1ALDH1A1L3MBTL1MAPK1
SCHEMBL18866856 0.82 SLC6A4 (0.43) SLC6A4TDP1ALDH1A1CYP3A4TP53
SCHEMBL7134261 0.81 SLC2A1 (0.43) SLC6A4MAPTMEN1KMT2ATDP1
SCHEMBL3863807 0.80 SLC6A4 (0.59) SLC6A4MAPTTDP1ALDH1A1CYP3A4
SCHEMBL3865060 0.80 SLC6A4 (0.59) SLC6A4MAPTTDP1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428891-B Curable composition 施敏打硬株式会社 2021-04-20 CN disclosed
CN-105392845-B Photocurable composition 思美定株式会社 2020-10-20 CN disclosed
EP-3081612-B1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES CEMEDINE CO LTD (JP) 2018-11-14 EP disclosed
US-9745406-B2 Curable composition CEMEDINE CO., LTD. (JP) 2017-08-29 US disclosed
US-9718999-B2 Photocurable composition having adhesive properties CEMEDINE CO., LTD (JP) 2017-08-01 US disclosed
EP-2412756-B1 CURABLE COMPOSITION CEMEDINE CO LTD (JP) 2016-12-21 EP disclosed
US-9481684-B2 Gonadotropin releasing hormone receptor antagonists, method for the preparation thereof and pharmaceutical composition comprising the same SK CHEMICALS CO., LTD. (KR) 2016-11-01 US disclosed
US-20160312089-A1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES CEMEDINE CO., LTD. (JP) 2016-10-27 US disclosed
EP-3081612-A1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES Cemedine Co., Ltd. (JP) 2016-10-19 EP disclosed
US-20160152783-A1 PHOTOCURABLE COMPOSITION CEMEDINE CO., LTD. (JP) 2016-06-02 US disclosed
CN-1252707-A Use of unsaturated aldehydes in dying fibers containing keratin HENKEL KGAA (DE) 2000-05-10 CN disclosed
EP-0611003-B1 Substituted phenyl sulfonamides as selective B3 agonists for the treatment of diabetes and obesity MERCK & CO INC (US) 1997-06-18 EP disclosed
US-5451677-A Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity MERCK & CO., INC. (US) 1995-09-19 US disclosed
EP-0611003-A1 Substituted phenyl sulfonamides as selective B3 agonists for the treatment of diabetes and obesity MERCK & CO. INC. (US) 1994-08-17 EP disclosed
US-5336749-A Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-08-09 US disclosed
EP-0394058-B1 ALICYCLIC DIAMINES, ALICYCLIC DIISOCYANATES AND POLYISOCYANATO-ISOCYANURATES AND METHOD FOR THE PREPARATION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-25 EP disclosed
US-5210286-A Hydrogenation of corresponding aromatic compound, reaction with phosgene MITSUI TOATSU CHEMICALS, INC. (JP) 1993-05-11 US disclosed
US-5126426-A Catalytic hydrogenation of aromatic diamine MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-06-30 US disclosed
CN-1046522-A Alicyclic diamine and vulcabond of alicyclic ring and polyisocyanate root close isocyanuric acid ester and preparation method thereof MITSUI TOATSU CHEMICALS (JP) 1990-10-31 CN disclosed
EP-0394058-A1 Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-10-24 EP disclosed