Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25367916 | 0.88 | ACSS2 (0.65) | ACSS2 | |
| SCHEMBL23843428 | 0.86 | ACSS2 (0.68) | ACSS2 | |
| SCHEMBL23843481 | 0.84 | ACSS2 (0.86) | ACSS2 | |
| SCHEMBL23843427 | 0.83 | ACSS2 (0.61) | ACSS2 | |
| SCHEMBL26046599 | 0.83 | ACSS2 (0.59) | ACSS2 | |
| SCHEMBL23843583 | 0.81 | ACSS2 (0.67) | ACSS2 | |
| SCHEMBL25366295 | 0.81 | ACSS2 (0.77) | ACSS2 | |
| SCHEMBL26046697 | 0.79 | ACSS2 (0.78) | ACSS2 | |
| SCHEMBL25366507 | 0.79 | ACSS2 (0.67) | ACSS2 | |
| SCHEMBL23843518 | 0.79 | ACSS2 (0.54) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021185789-A1 | CONDENSED PYRIDINE DERIVASTIVES SUBSTITUED BY AMIDE FUNCTIONS AS ACSS2 INHIBITORS | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |