Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 16/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 2/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23843504 | 0.90 | ACSS2 (0.54) | ACSS2ALDH1A1MAPTRAB9A | |
| SCHEMBL23843476 | 0.88 | ACSS2 (0.47) | ACSS2ALDH1A1MAPTRAB9ASCD | |
| SCHEMBL23843440 | 0.88 | ACSS2 (0.53) | ACSS2 | |
| SCHEMBL25368422 | 0.84 | ACSS2 (0.60) | ACSS2 | |
| SCHEMBL18675084 | 0.81 | ACSS2 (0.71) | ACSS2 | |
| SCHEMBL23843434 | 0.79 | ACSS2 (0.48) | ACSS2ALDH1A1SCDSCD5 | |
| SCHEMBL25367850 | 0.79 | ACSS2 (0.69) | ACSS2 | |
| SCHEMBL25367344 | 0.78 | ACSS2 (0.58) | ACSS2 | |
| SCHEMBL23843439 | 0.77 | ACSS2 (0.54) | ACSS2ALDH1A1SCD5 | |
| SCHEMBL30640949 | 0.77 | ACSS2 (0.54) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021185789-A1 | CONDENSED PYRIDINE DERIVASTIVES SUBSTITUED BY AMIDE FUNCTIONS AS ACSS2 INHIBITORS | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |