Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.51 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.48 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.48 |
| ▸ | GJA1 | P17302 | 1/20 | 0.47 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | AMY2A | P04746 | 1/20 | 0.44 |
| ▸ | IGF2R | P11717 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23126082 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL16587626 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL13078069 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL12127166 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL23844351 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL12129496 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL19682223 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL15130864 | 0.98 | MEN1 (0.51) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL15132503 | 0.98 | MEN1 (0.51) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL19682224 | 0.98 | MEN1 (0.51) | MEN1KMT2AAMY1ALGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188456-A1 | ENASIDENIB GLYCOSIDES AND METHODS OF TREATING DISEASES ASSOCIATED WITH ISOCITRATE DEHYDROGENASE (IDH) DYSFUNCTION | DOUBLERAINBOW BIOSCIENCES INC. (US) | 2021-09-23 | — | — | WO | disclosed |