Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.51 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.48 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.48 |
| ▸ | GJA1 | P17302 | 1/20 | 0.47 |
| ▸ | GJB2 | P29033 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | AMY2A | P04746 | 1/20 | 0.44 |
| ▸ | IGF2R | P11717 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23126082 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL13078069 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL12127166 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL23844351 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL12129496 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL23844387 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL19682223 | 1.00 | MEN1 (0.52) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL15130864 | 0.98 | MEN1 (0.51) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL15132503 | 0.98 | MEN1 (0.51) | MEN1KMT2AAMY1ALGALS8LGALS3 | |
| SCHEMBL19682224 | 0.98 | MEN1 (0.51) | MEN1KMT2AAMY1ALGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013767-A1 | REBAUDIOSIDE ANALOGS | PEPSICO, INC. (US) | 2018-01-18 | — | — | WO | disclosed |
| US-9629865-B2 | Modified saponins for the treatment of fungal infections | THE BROAD INSTITUTE, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-20160228465-A1 | Modified Saponins For the Treatment of Fungal Infections | NIH - DEITR | 2016-08-11 | — | — | US | disclosed |
| US-9320751-B2 | Modified saponins for the treatment of fungal infections | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-26 | — | — | US | disclosed |
| US-20150182544-A1 | Modified Saponins for the Treatment of Fungal Infections | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2015-07-02 | — | — | US | disclosed |
| US-20150157721-A1 | POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY | LIPOSEUTICALS INC | 2015-06-11 | — | — | US | disclosed |
| US-8987217-B2 | Modified saponins for the treatment of fungal infections | THE GENERAL HOSPITAL CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150182544-A1 | Modified Saponins for the Treatment of Fungal Infections | ERG28, TREH, MANBA | MEN1 1850/4885KMT2A 2336/4885AMY1A 227/4885 |
| US-20160228465-A1 | Modified Saponins For the Treatment of Fungal Infections | ERG28, TREH, MANBA | MEN1 1850/4885KMT2A 2336/4885AMY1A 227/4885 |
| US-20150157721-A1 | POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY | LIPC, FABP4, CETP | MEN1 2733/4885KMT2A 1977/4885AMY1A 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.