Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833146 | 0.91 | AAK1 (0.39) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL23833150 | 0.91 | AAK1 (0.39) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL23832922 | 0.90 | AAK1 (0.39) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL23832924 | 0.90 | AAK1 (0.39) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL22526040 | 0.87 | AAK1 (0.40) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL22526813 | 0.83 | LTB4R (0.39) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL23833101 | 0.83 | LTB4R (0.39) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL23845226 | 0.83 | AAK1 (0.37) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL22526904 | 0.82 | AAK1 (0.43) | AAK1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL23833084 | 0.82 | AAK1 (0.40) | AAK1HDAC1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |