Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901572 | 1.00 | EPHX1 (0.57) | EPHX1CARM1PRMT6EPHX2APP | |
| SCHEMBL22393075 | 1.00 | EPHX1 (0.57) | EPHX1CARM1PRMT6EPHX2APP | |
| SCHEMBL901540 | 1.00 | EPHX1 (0.57) | EPHX1CARM1PRMT6EPHX2APP | |
| SCHEMBL9679337 | 0.98 | EPHX1 (0.54) | EPHX1CARM1PRMT6EPHX2APP | |
| SCHEMBL872221 | 0.94 | CARM1 (0.54) | EPHX1CARM1PRMT6EPHX2APP | |
| Hydrogen Sulfide SCHEMBL15066150 | 0.92 | CARM1 (0.53) | EPHX1CARM1PRMT6EPHX2APP | |
| Water SCHEMBL15066370 | 0.92 | CARM1 (0.53) | EPHX1CARM1PRMT6EPHX2APP | |
| SCHEMBL10055002 | 0.89 | CARM1 (0.57) | EPHX1CARM1PRMT6MEN1KMT2A | |
| SCHEMBL18434523 | 0.89 | CARM1 (0.57) | EPHX1CARM1PRMT6MEN1KMT2A | |
| SCHEMBL10055063 | 0.89 | CARM1 (0.57) | EPHX1CARM1PRMT6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188696-A1 | STAT DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |