SCHEMBL9679337

SCHEMBL9679337

c1ccc(NCC2CCCC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.54
CARM1 Q86X55 1/20 0.54
PRMT6 Q96LA8 1/20 0.54
EPHX2 P34913 1/20 0.49
APP P05067 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
KCNH3 Q9ULD8 1/20 0.45
CRHR1 P34998 1/20 0.44
ACHE P22303 1/20 0.44
BACE1 P56817 1/20 0.44
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.43
ALDH3A1 P30838 1/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.42
KDM4C Q9H3R0 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901572 0.98 EPHX1 (0.57) EPHX1CARM1PRMT6EPHX2APP
SCHEMBL22393075 0.98 EPHX1 (0.57) EPHX1CARM1PRMT6EPHX2APP
SCHEMBL901540 0.98 EPHX1 (0.57) EPHX1CARM1PRMT6EPHX2APP
SCHEMBL23845320 0.98 EPHX1 (0.57) EPHX1CARM1PRMT6EPHX2APP
SCHEMBL872221 0.96 CARM1 (0.54) EPHX1CARM1PRMT6EPHX2APP
Hydrogen Sulfide SCHEMBL15066150 0.94 CARM1 (0.53) EPHX1CARM1PRMT6EPHX2APP
Water SCHEMBL15066370 0.94 CARM1 (0.53) EPHX1CARM1PRMT6EPHX2APP
SCHEMBL10055002 0.91 CARM1 (0.57) EPHX1CARM1PRMT6SMN1; SMN2NPC1
SCHEMBL18434523 0.91 CARM1 (0.57) EPHX1CARM1PRMT6SMN1; SMN2NPC1
SCHEMBL10055063 0.91 CARM1 (0.57) EPHX1CARM1PRMT6SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795315-B2 Group 5 metal complexes for producing amine-functionalized polyolefins THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-10-24 US disclosed
US-11795315-B2 Group 5 metal complexes for producing amine-functionalized polyolefins THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-10-24 US disclosed
US-20220363786-A1 GROUP 5 METAL COMPLEXES FOR PRODUCING AMINE-FUNTIONALIZED POLYOLEFINS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-11-17 US disclosed
US-20220363786-A1 GROUP 5 METAL COMPLEXES FOR PRODUCING AMINE-FUNTIONALIZED POLYOLEFINS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-11-17 US disclosed
US-11034707-B2 Group 5 metal complexes for catalytic amine functionalization THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-06-15 US disclosed
US-11034707-B2 Group 5 metal complexes for catalytic amine functionalization THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-06-15 US disclosed
US-20200283459-A1 GROUP 5 METAL COMPLEXES FOR CATALYTIC AMINE FUNCTIONALIZATION THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2020-09-10 US disclosed
US-20200283459-A1 GROUP 5 METAL COMPLEXES FOR CATALYTIC AMINE FUNCTIONALIZATION THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2020-09-10 US disclosed
EP-3508477-A1 C5AR ANTAGONISTS ChemoCentryx, Inc. (US) 2019-07-10 EP disclosed
US-5153226-A Administering as anticholesterol agents, for atherosclerosis WARNER-LAMBERT COMPANY (US) 1992-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200283459-A1 GROUP 5 METAL COMPLEXES FOR CATALYTIC AMINE FUNCTIONALIZATION ADH5, PRMT5, MAOA EPHX1 1809/4885CARM1 60/4885PRMT6 38/4885
US-11034707-B2 Group 5 metal complexes for catalytic amine functionalization ADH5, PRMT5, MAOA EPHX1 1809/4885CARM1 60/4885PRMT6 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.