Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145839 | 0.76 | — | — | |
| SCHEMBL29978927 | 0.76 | — | — | |
| SCHEMBL10280707 | 0.75 | PIK3CD (0.41) | MAPTCHRNA3PIK3CDNAPRTPOLB | |
| SCHEMBL1145837 | 0.71 | — | — | |
| SCHEMBL21288402 | 0.71 | — | — | |
| SCHEMBL29687635 | 0.71 | DGAT1 (0.41) | MAPTPIK3CDNAPRTDGAT1ALDH1A1 | |
| SCHEMBL23845466 | 0.71 | DGAT1 (0.37) | PIK3CDNAPRTPOLBDGAT1 | |
| SCHEMBL23833573 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2PIK3CDNAPRTPOLBDGAT1 | |
| SCHEMBL30094648 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2PIK3CDNAPRTPOLBDGAT1 | |
| SCHEMBL16676162 | 0.71 | DGAT1 (0.41) | MAPTPIK3CDNAPRTDGAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188938-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | AKEBIA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |