SCHEMBL2384564

SCHEMBL2384564

CN(C)c1ccc(/N=N/c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.64
MAPK1 P28482 6/20 0.64
TSHR P16473 4/20 0.64
TDP1 Q9NUW8 3/20 0.64
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
PHLPP2 Q6ZVD8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
NPC1 O15118 7/20 0.59
MEN1 O00255 7/20 0.59
KMT2A Q03164 7/20 0.59
RAB9A P51151 6/20 0.59
TNNI3 P19429 1/20 0.59
TNNT2 P45379 1/20 0.59
TNNC1 P63316 1/20 0.59
KEAP1 Q14145 1/20 0.59
NFE2L2 Q16236 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MMP14 P50281 1/20 0.57
ALDH1A1 P00352 5/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7987030 1.00 MAPT (0.64) MAPTMAPK1TSHRTDP1CYP1A2
SCHEMBL2384567 1.00 MAPT (0.64) MAPTMAPK1TSHRTDP1CYP1A2
SCHEMBL7987027 1.00 MAPT (0.64) MAPTMAPK1TSHRTDP1CYP1A2
SCHEMBL218018 0.88 MAPT (0.78) MAPTMAPK1TSHRTDP1CYP1A2
Phosphine SCHEMBL30201038 0.86 MAPT (0.75) MAPTMAPK1TSHRTDP1CYP1A2
Ammonia Solution, Strong SCHEMBL29558993 0.86 MAPT (0.75) MAPTMAPK1TSHRTDP1CYP1A2
Hydrogen Sulfide SCHEMBL28326954 0.86 MAPT (0.75) MAPTMAPK1TSHRTDP1CYP1A2
SCHEMBL18025268 0.84 MAPT (0.49) MAPTMAPK1TSHRTDP1CYP1A2
Iodide SCHEMBL10484653 0.84 MAPT (0.72) MAPTMAPK1TSHRTDP1CYP1A2
SCHEMBL3282773 0.84 MEN1 (0.61) MAPTMAPK1TDP1NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006060654-A2 PESTICIDAL COMPOSITIONS AND METHODS DIVERGENCE, INC. (US) 2006-06-08 WO claimed
US-20050203067-A1 Pesticidal compositions and methods DIVERGENCE, INC. 2005-09-15 US claimed
US-5371122-A Resolution, colorant dispersed without aggregation MITSUBOSHI BELTING LTD. (JP) 1994-12-06 US claimed
US-4904569-A Method of forming pattern and projection aligner for carrying out the same HITACHI, LTD. (JP) 1990-02-27 US claimed
WO-2024256678-A1 COLORIMETRIC DETECTION DEVICE IN THE FORM OF A SPRAYER FOR THE DETECTION OF CHEMICAL COMPOUNDS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2024-12-19 WO disclosed
EP-4449102-A1 DETECTION SYSTEM FOR THE DETECTION OF (A) CHEMICAL COMPOUND(S) BASED ON DISTINCT PARTICLES IMPREGNATED WITH DISTINCT DETECTION INDICATORS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2024-10-23 EP disclosed
WO-2023111475-A1 DETECTION SYSTEM SUITABLE FOR USE IN THE DETECTION OF CHEMICAL COMPOUNDS COMPRISING A DETECTION STRIP COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-06-22 WO disclosed
WO-2023111474-A1 DETECTION SYSTEM FOR THE DETECTION OF (A) CHEMICAL COMPOUND(S) BASED ON DISTINCT PARTICLES IMPREGNATED WITH DISTINCT DETECTION INDICATORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-06-22 WO disclosed
US-9575246-B2 Prepolymer, curable material, coating composition, non-linear optical material, optical waveguide and light control device ASAHI GLASS COMPANY, LIMITED (JP) 2017-02-21 US disclosed
US-20150153509-A1 PREPOLYMER, CURABLE MATERIAL, COATING COMPOSITION, NON-LINEAR OPTICAL MATERIAL, OPTICAL WAVEGUIDE AND LIGHT CONTROL DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2015-06-04 US disclosed
EP-1944332-B1 Method of modifying surface layer of molded resin NAT INST OF ADVANCED IND SCIEN (JP) 2012-08-08 EP disclosed
US-8026021-B2 Film forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of the said material Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2011-09-27 US disclosed
EP-0868682-A1 ELECTRO- OR OPTO-OPTICAL DEVICE STABLE IN THE 600-1600 NANOMETER WAVELENGTH RANGE Akzo Nobel N.V. (NL) 1998-10-07 EP disclosed
WO-1997023807-A1 ELECTRO- OR OPTO-OPTICAL DEVICE STABLE IN THE 600-1600 NANOMETER WAVELENGTH RANGE AKZO NOBEL N.V. (NL) 1997-07-03 WO disclosed
US-5371122-A Resolution, colorant dispersed without aggregation MITSUBOSHI BELTING LTD. (JP) 1994-12-06 US disclosed
US-5334333-A Permanent change in refractive index due to exposure to optic radiation ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-02 US disclosed
EP-0491364-A2 Electroactive compounds, compositions and devices and methods of making the same ATOCHEM NORTH AMERICA, INC. (US) 1992-06-24 EP disclosed
US-4904569-A Method of forming pattern and projection aligner for carrying out the same HITACHI, LTD. (JP) 1990-02-27 US disclosed
US-4613208-A ELECTROOPTICS; ULTRAVIOLET RADIATION STABILITY; QUICK RESPONSE HOFFMANN-LA ROCHE INC. (US) 1986-09-23 US disclosed
US-4081278-A AND A REDUCIBLE DYE OR DYE PRECURSOR EASTMAN KODAK COMPANY (US) 1978-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203067-A1 Pesticidal compositions and methods ACHE, DDT, PTMS MAPT 3378/4885MAPK1 4785/4885TSHR 2997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.