Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18072166 | 1.00 | GAA (0.38) | GAAHTTCYP2D6LMNA | |
| SCHEMBL7506478 | 0.94 | GAA (0.41) | GAAHTTCYP2D6LMNA | |
| SCHEMBL30795 | 0.94 | CYP2D6 (0.35) | GAAHTTCYP2D6LMNA | |
| SCHEMBL20113386 | 0.94 | CYP2D6 (0.35) | GAAHTTCYP2D6LMNA | |
| SCHEMBL13842572 | 0.89 | CYP2D6 (0.33) | CYP2D6LMNA | |
| SCHEMBL14274507 | 0.89 | CYP2D6 (0.33) | GAACYP2D6LMNA | |
| SCHEMBL21675508 | 0.88 | GAA (0.37) | GAAHTTCYP2D6LMNA | |
| SCHEMBL22426085 | 0.88 | GAA (0.37) | GAAHTTCYP2D6LMNA | |
| SCHEMBL16790838 | 0.88 | GAA (0.37) | GAAHTTCYP2D6LMNA | |
| SCHEMBL24337246 | 0.88 | GAA (0.37) | GAAHTTCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292652-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292652-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | CXCR1, PYM1, F11 | GAA 4668/4885HTT 4108/4885CYP2D6 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.