Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.56 |
| ▸ | CNR1 | P21554 | 3/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RHOC | P08134 | 1/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754353 | 0.79 | ABL1 (0.56) | ABL1CNR1CNR2L3MBTL1MEN1 | |
| SCHEMBL23846502 | 0.76 | TP53 (0.50) | CNR1L3MBTL1METMEN1KMT2A | |
| SCHEMBL23846538 | 0.74 | KDR (0.51) | L3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL30469231 | 0.73 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL20557634 | 0.73 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL23846640 | 0.72 | KCNQ3 (0.46) | L3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL15392021 | 0.72 | ABL1 (1.00) | ABL1MET | |
| SCHEMBL23846647 | 0.71 | RAB9A (0.45) | L3MBTL1GRM5NPC1RAB9AMEN1 | |
| SCHEMBL23846539 | 0.71 | NPC1 (0.55) | L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL15392868 | 0.71 | ABL1 (0.69) | ABL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188880-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |