Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29786780 | 1.00 | CETP (0.53) | CETPNR1I2CASR | |
| SCHEMBL5165035 | 0.87 | CETP (0.54) | CETPNR1I2CASR | |
| SCHEMBL5165026 | 0.85 | CETP (0.53) | CETPNR1I2CASR | |
| SCHEMBL4154599 | 0.83 | CETP (0.53) | CETPNR1I2CASR | |
| SCHEMBL531538 | 0.83 | CETP (0.61) | CETPNR1I2 | |
| SCHEMBL531379 | 0.82 | CETP (0.63) | CETPNR1I2 | |
| SCHEMBL133988 | 0.82 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL17965460 | 0.82 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL132467 | 0.82 | CETP (0.53) | CETPNR1I2CASR | |
| SCHEMBL532052 | 0.82 | CETP (0.53) | CETPNR1I2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210290623-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | DALCOR PHARMA UK LTD., LEATHERHEAD, ZUG BRANCH (CH) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210290623-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | HMGCR, PCSK9, FABP3 | CETP 10/4885NR1I2 3082/4885CASR 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.