Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.53 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165035 | 0.84 | CETP (0.54) | CETPCASRNR1I2 | |
| SCHEMBL23846705 | 0.83 | CETP (0.53) | CETPCASRNR1I2 | |
| SCHEMBL29786780 | 0.83 | CETP (0.53) | CETPCASRNR1I2 | |
| SCHEMBL5165026 | 0.82 | CETP (0.53) | CETPCASRNR1I2 | |
| SCHEMBL531538 | 0.80 | CETP (0.61) | CETPNR1I2 | |
| SCHEMBL10110458 | 0.79 | CETP (0.58) | CETPNR1I2 | |
| SCHEMBL17965460 | 0.79 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL133988 | 0.79 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL531379 | 0.79 | CETP (0.63) | CETPNR1I2 | |
| SCHEMBL132467 | 0.79 | CETP (0.53) | CETPCASRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737811-A4 | CETP INHIBITORS | MERCK & CO INC (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1737811-A1 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100298-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2005-10-27 | — | — | WO | disclosed |