Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22011764 | 0.75 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTGLAKDM4E | |
| SCHEMBL9748738 | 0.73 | MAPK1 (0.45) | ALDH1A1L3MBTL1HTTGLAKDM4E | |
| SCHEMBL19474937 | 0.70 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTKDM4EGAA | |
| SCHEMBL22905417 | 0.70 | — | — | |
| SCHEMBL22905486 | 0.70 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1HTTGLAKDM4E | |
| SCHEMBL20933020 | 0.70 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1HTTGLAKDM4E | |
| SCHEMBL23847349 | 0.70 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTGLAKDM4E | |
| SCHEMBL22899683 | 0.70 | HTT (0.47) | ALDH1A1L3MBTL1HTTGLAKDM4E | |
| SCHEMBL9748593 | 0.68 | MAPK1 (0.50) | ALDH1A1L3MBTL1HTTGLAKDM4E | |
| SCHEMBL24016786 | 0.65 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1HTTGLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188450-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD (US) | 2021-09-23 | — | — | WO | disclosed |