Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891021 | 0.69 | DAO (0.41) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5358324 | 0.64 | DAO (0.38) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11401866 | 0.64 | DAO (0.38) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6900668 | 0.64 | DAO (0.38) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9134716 | 0.62 | DAO (0.44) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2574210 | 0.62 | DAO (0.35) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19237422 | 0.62 | — | — | |
| SCHEMBL28377995 | 0.60 | PARP1 (0.44) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14469275 | 0.60 | DAO (0.33) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19013294 | 0.60 | CYSLTR2 (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188450-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD (US) | 2021-09-23 | — | — | WO | disclosed |