Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891021 | 0.70 | DAO (0.41) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5358324 | 0.65 | DAO (0.38) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6900668 | 0.65 | DAO (0.38) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11051645 | 0.64 | ALDH1A1 (0.59) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9134716 | 0.64 | DAO (0.44) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL23847374 | 0.64 | DAO (0.36) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2574210 | 0.64 | DAO (0.35) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11400539 | 0.62 | — | — | |
| SCHEMBL28377995 | 0.61 | PARP1 (0.44) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11400413 | 0.61 | GRIN2D (0.35) | DAOGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032048-A1 | Pyrroloylpyrrole derivatives, processes for their preparation and their use | BEECHAM GROUP PLC (GB) | 1981-07-15 | — | — | EP | claimed |
| EP-0032048-A1 | Pyrroloylpyrrole derivatives, processes for their preparation and their use | BEECHAM GROUP PLC (GB) | 1981-07-15 | — | — | EP | disclosed |