Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CALML3 | P27482 | 1/20 | 0.40 |
| ▸ | SDHA | P31040 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18410530 | 0.84 | MAOA (0.59) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL24169210 | 0.84 | MAOA (0.59) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL18408852 | 0.84 | MAOB (0.59) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL24169485 | 0.84 | MAOB (0.52) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL24296584 | 0.84 | CALML3 (0.51) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL4015562 | 0.84 | MAOA (0.50) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL18408850 | 0.82 | MAOB (0.56) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL18410646 | 0.82 | MAOB (0.56) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL18410536 | 0.82 | MAOA (0.48) | MAOAMAOBLMNAPTGS1CALML3 | |
| SCHEMBL18410647 | 0.82 | MAOB (0.60) | MAOAMAOBLMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188606-A1 | OXAZOLIDINONE COMPOUND AND METHODS OF USE THEREOF AS AN ANTIBACTERIAL AGENT | MERCK SHARP & DOHME CORP. (US) | 2021-09-23 | — | — | WO | disclosed |