Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23835255 | 0.84 | L3MBTL1 (0.40) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL31267284 | 0.83 | MEN1 (0.40) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL23835297 | 0.82 | MEN1 (0.44) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL411707 | 0.75 | MEN1 (0.41) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL29168261 | 0.75 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL19304000 | 0.75 | NPC1 (0.46) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL13642501 | 0.75 | KDM4E (0.46) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL1345450 | 0.75 | KDM4C (0.49) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL1629524 | 0.74 | S1PR4 (0.43) | L3MBTL1MEN1KMT2AKDM4CNPC1 | |
| SCHEMBL22031112 | 0.74 | MEN1 (0.42) | L3MBTL1MEN1KMT2AKDM4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021186324-A1 | BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS | NOVARTIS AG (CH) | 2021-09-23 | — | — | WO | disclosed |