⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410383 | 0.85 | — | — | |
| SCHEMBL15743714 | 0.82 | MEN1 (0.36) | — | |
| SCHEMBL13671440 | 0.77 | — | — | |
| SCHEMBL18902642 | 0.77 | — | — | |
| SCHEMBL8909834 | 0.75 | MEN1 (0.35) | — | |
| SCHEMBL15127356 | 0.75 | — | — | |
| SCHEMBL13646073 | 0.75 | PIK3CD (0.41) | — | |
| SCHEMBL13304001 | 0.73 | — | — | |
| SCHEMBL438244 | 0.72 | — | — | |
| SCHEMBL6974724 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| US-20210292331-A1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2021-09-23 | — | — | US | disclosed |