SCHEMBL8909834

SCHEMBL8909834

CC(C)N(C)CCN(C)C(C)C

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24424824 0.89 CA12 (0.44) MEN1KMT2AHTR2A
SCHEMBL21955607 0.89 HTR2A (0.31) MEN1KMT2AHTR2A
SCHEMBL2737210 0.89 CA12 (0.44) MEN1KMT2AHTR2A
SCHEMBL21127039 0.87
SCHEMBL24424697 0.87
SCHEMBL12791352 0.87 MEN1 (0.48) MEN1KMT2A
SCHEMBL5715676 0.85 MEN1 (0.32) MEN1KMT2AHTR2A
SCHEMBL22790537 0.84 HTR2A (0.36) HTR2A
SCHEMBL24218580 0.84
SCHEMBL25765922 0.84 AOC3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238076-A1 PROCESS FOR PRODUCING VASCULAR PROSTHESES LUDWIG BOLTZMANN GESELLSCHAFT – ÖSTERREICHISCHE VEREINIGUNG ZUR FÖRDERUNG VON WISSENSCHAFTLICHEN FORSCHUNGEN (AT) 2024-07-18 US disclosed
US-20240216513-A1 FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE NOVARTIS AG (CH) 2024-07-04 US disclosed
US-20240216513-A1 FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE NOVARTIS AG (CH) 2024-07-04 US disclosed
US-11807636-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-11-07 US disclosed
US-20230272148-A1 THERMOPLASTIC POLY(URETHANE-UREA) POLYADDUCTS TECHNISCHE UNIVERSITAET WIEN (AT) 2023-08-31 US disclosed
US-20230212549-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2023-07-06 US disclosed
US-20230203063-A1 TRICYCLIC PYRIDONES AND PYRIMIDONES ERASCA, INC. 2023-06-29 US disclosed
US-20230159563-A1 TRICYCLIC PYRIDONES AND PYRIMIDONES ERASCA, INC. 2023-05-25 US disclosed
US-20230158141-A1 Conjugates of Biomolecule and Use Thereof YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOG (CN) 2023-05-25 US disclosed
US-20230158141-A1 Conjugates of Biomolecule and Use Thereof YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOG (CN) 2023-05-25 US disclosed
US-20110052673-A1 THERAPEUTIC COMPOSITIONS SHIRE HUMAN GENETIC THERAPIES, INC. 2011-03-03 US disclosed
US-20110009641-A1 Amine-containing lipids and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-01-13 US disclosed
US-20100260715-A1 HEPATITIS C VIRUS INHIBITORS ENANTA PHARMACEUTICALS, INC. 2010-10-14 US disclosed
US-20100233122-A1 NOVEL BENZIMIDAZOLE DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2010-09-16 US disclosed
US-20100221214-A1 LINKED DIBENZIMIDAZOLE DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2010-09-02 US disclosed
US-7494991-B2 Rifamycin analogs and uses thereof ACTIVBIOTICS PHARMA, LLC (US) 2009-02-24 US disclosed
US-20070238747-A1 Rifamycin analogs and uses thereof ACTIVBIOTICS, INC. (US) 2007-10-11 US disclosed
US-20070142392-A1 Uses of rifamycins ACTIVBIOTICS, INC. (US) 2007-06-21 US disclosed
WO-2007070084-A1 USES OF RIFAMYCINS ACTIVBIOTICS, INC. (US) 2007-06-21 WO disclosed
US-7220738-B2 Rifamycin analogs and uses thereof ACTIVBIOTICS, INC. (US) 2007-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212549-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF FIBP, FN1, TPX2 MEN1 2450/4885KMT2A 3476/4885HTR2A 4326/4885
US-20230203063-A1 TRICYCLIC PYRIDONES AND PYRIMIDONES TYMS, TYMP, DHFR MEN1 868/4885KMT2A 3204/4885HTR2A 911/4885
US-20070142392-A1 Uses of rifamycins TNF, TLR6, IL6 MEN1 3624/4885KMT2A 3755/4885HTR2A 4832/4885
US-20100260715-A1 HEPATITIS C VIRUS INHIBITORS HAVCR2, SLC10A1, EIF2AK2 MEN1 4782/4885KMT2A 2957/4885HTR2A 4663/4885
US-20100233122-A1 NOVEL BENZIMIDAZOLE DERIVATIVES EIF2AK2, ZC3HAV1, HAVCR2 MEN1 4868/4885KMT2A 1865/4885HTR2A 4601/4885
US-20240216513-A1 FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE FASN, FABP1, SCD MEN1 4331/4885KMT2A 2000/4885HTR2A 2305/4885
US-20110052673-A1 THERAPEUTIC COMPOSITIONS PHOSPHO1, SGMS1, APOB MEN1 718/4885KMT2A 2906/4885HTR2A 1745/4885
US-20230158141-A1 Conjugates of Biomolecule and Use Thereof CD47, FCGR2A, CD40 MEN1 2859/4885KMT2A 2284/4885HTR2A 3413/4885
US-20110009641-A1 Amine-containing lipids and uses thereof PHOSPHO1, CHMP4B, SGMS1 MEN1 1363/4885KMT2A 2031/4885HTR2A 2189/4885
US-20100221214-A1 LINKED DIBENZIMIDAZOLE DERIVATIVES EIF2AK2, NSUN2, ZC3HAV1 MEN1 4801/4885KMT2A 2014/4885HTR2A 4796/4885
US-11807636-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK1 MEN1 4055/4885KMT2A 445/4885HTR2A 3621/4885
US-20230159563-A1 TRICYCLIC PYRIDONES AND PYRIMIDONES KRAS, NRAS, HRAS MEN1 1339/4885KMT2A 1375/4885HTR2A 4122/4885
US-20070238747-A1 Rifamycin analogs and uses thereof RIF1, HDAC5, HDAC4 MEN1 4056/4885KMT2A 1979/4885HTR2A 4123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.