SCHEMBL23848909 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	PIK3CA	P42336	8/20	0.51

▸	PIK3CD	O00329	4/20	0.51

▸	MTOR	P42345	4/20	0.45

▸	ATR	Q13535	11/20	0.42

▸	CHEK1	O14757	10/20	0.42

▸	PDCD1	Q15116	10/20	0.42

▸	ATRIP	Q8WXE1	10/20	0.42

▸	CD274	Q9NZQ7	10/20	0.42

▸	ATM	Q13315	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23848911	0.86	PIK3CA (0.53)	PIK3CAPIK3CDMTORATRCHEK1
SCHEMBL23848912	0.79	ATR (0.51)	PIK3CAMTORATRATRIPATM
SCHEMBL23848913	0.78	ATR (0.48)	PIK3CAMTORATRATRIPATM
SCHEMBL23848906	0.78	ATR (0.47)	PIK3CAMTORATRATRIPATM
SCHEMBL739607	0.76	PIK3CA (0.52)	PIK3CAPIK3CDMTORATRCHEK1
SCHEMBL23849053	0.75	PIK3CA (0.54)	PIK3CAPIK3CDATRCHEK1PDCD1
SCHEMBL1270892	0.74	MTOR (0.63)	PIK3CAPIK3CDMTORATRATM
SCHEMBL23848905	0.72	ATR (0.58)	PIK3CAMTORATRATRIPATM
SCHEMBL23848949	0.72	ATR (0.50)	PIK3CAMTORATRATRIPATM
SCHEMBL26960994	0.72	KMT2A (0.47)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021189036-A1	TAF1 INHIBITORS	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US)	2021-09-23	—	—	WO	disclosed