SCHEMBL23850144

SCHEMBL23850144

CC(c1ccccc1)N1CCC1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 7/20 0.83
MC4R P32245 1/20 0.70
OPRM1 P35372 6/20 0.58
OPRK1 P41145 3/20 0.58
OPRL1 P41146 3/20 0.58
OPRD1 P41143 2/20 0.58
KCNH2 Q12809 6/20 0.56
CYP3A4 P08684 5/20 0.56
CYP1A2 P05177 4/20 0.56
CYP2C9 P11712 4/20 0.56
KCNA5 P22460 4/20 0.56
CYP2C19 P33261 4/20 0.56
KCNE1 P15382 1/20 0.54
ALDH1A1 P00352 2/20 0.51
CHRM2 P08172 5/20 0.49
CHRM1 P11229 5/20 0.49
LTA4H P09960 1/20 0.46
LMNA P02545 1/20 0.46
ADRA2A P08913 2/20 0.45
DRD1 P21728 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31046801 1.00 CYP2D6 (0.83) CYP2D6MC4ROPRM1OPRK1OPRL1
SCHEMBL30364156 1.00 CYP2D6 (0.83) CYP2D6MC4ROPRM1OPRK1OPRL1
SCHEMBL7097730 0.95 CYP2D6 (0.83) CYP2D6MC4ROPRM1OPRK1OPRL1
SCHEMBL8983627 0.95 CYP2D6 (0.83) CYP2D6MC4ROPRM1OPRK1OPRL1
SCHEMBL8983562 0.95 CYP2D6 (0.83) CYP2D6MC4ROPRM1OPRK1OPRL1
SCHEMBL20191913 0.93 CYP2D6 (0.79) CYP2D6MC4ROPRM1OPRK1OPRL1
SCHEMBL2631769 0.93 CYP2D6 (0.79) CYP2D6MC4ROPRM1OPRK1OPRL1
SCHEMBL1406105 0.93 CYP2D6 (0.79) CYP2D6MC4ROPRM1OPRK1OPRL1
Hydrochloric Acid SCHEMBL10551490 0.91 CYP2D6 (0.76) CYP2D6MC4ROPRM1OPRK1OPRL1
Bromide SCHEMBL28217352 0.91 CYP2D6 (0.76) CYP2D6MC4ROPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3883925-A1 CYCLIC UREAS Sironax Ltd (KY) 2021-09-29 EP disclosed