Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.76 |
| ▸ | MC4R | P32245 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.61 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.61 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20191913 | 0.98 | CYP2D6 (0.79) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2631769 | 0.98 | CYP2D6 (0.79) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1406105 | 0.98 | CYP2D6 (0.79) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL10551490 | 0.96 | CYP2D6 (0.76) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8983627 | 0.96 | CYP2D6 (0.83) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7097730 | 0.96 | CYP2D6 (0.83) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8983562 | 0.96 | CYP2D6 (0.83) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23850144 | 0.91 | CYP2D6 (0.83) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31046801 | 0.91 | CYP2D6 (0.83) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30364156 | 0.91 | CYP2D6 (0.83) | CYP2D6MC4RCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586723-A | Polycondensation resin and optical film formed therefrom | 三菱化学株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-106062035-B | Polycondensation resin and optical film formed therefrom | 三菱化学株式会社 | 2018-05-29 | — | — | CN | disclosed |