SCHEMBL23850644

SCHEMBL23850644

NC(CCCCB(O)O)(C(=O)O)C1CCN(CCc2c(F)cccc2F)CC1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 20/20 0.65
ARG2 P78540 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23850294 0.88 ARG1 (0.72) ARG1ARG2
SCHEMBL894867 0.85 ARG1 (0.80) ARG1ARG2
SCHEMBL27903250 0.85 ARG1 (0.80) ARG1ARG2
Hydrochloric Acid SCHEMBL27921005 0.85 ARG1 (0.78) ARG1ARG2
SCHEMBL894939 0.84 ARG1 (0.68) ARG1ARG2
SCHEMBL30169823 0.84 ARG1 (0.68) ARG1ARG2
Hydrochloric Acid SCHEMBL895923 0.83 ARG1 (0.67) ARG1ARG2
SCHEMBL894654 0.82 ARG1 (0.80) ARG1ARG2
SCHEMBL23850336 0.82 ARG1 (0.71) ARG1ARG2
SCHEMBL23850018 0.82 ARG1 (0.77) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3883938-A1 INHIBITORS OF ARGINASE Praxis Biotech LLC (US) 2021-09-29 EP disclosed