Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | HTT | P42858 | 2/20 | 0.79 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.56 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399012 | 0.97 | SMN1; SMN2 (0.84) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL830176 | 0.95 | SMN1; SMN2 (0.88) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL31323057 | 0.86 | SMN1; SMN2 (0.88) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL30559852 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL23850681 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL30559858 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL31323039 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL3077817 | 0.80 | SMN1; SMN2 (0.72) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL23199839 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AMAPTHTT | |
| SCHEMBL829826 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883925-A1 | CYCLIC UREAS | Sironax Ltd (KY) | 2021-09-29 | — | — | EP | disclosed |