Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23199827 | 0.99 | SMN1; SMN2 (0.51) | SMN1; SMN2HTTMAPTMEN1KMT2A | |
| SCHEMBL29965291 | 0.84 | TSHR (0.51) | SMN1; SMN2HTTMAPTMEN1KMT2A | |
| SCHEMBL29965137 | 0.84 | TSHR (0.51) | SMN1; SMN2HTTMAPTMEN1KMT2A | |
| SCHEMBL23850682 | 0.80 | SMN1; SMN2 (0.79) | SMN1; SMN2HTTMAPTMEN1KMT2A | |
| SCHEMBL30628898 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTMAPTMEN1KMT2A | |
| SCHEMBL12467310 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTMAPTMEN1KMT2A | |
| SCHEMBL30628897 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTMAPTMEN1KMT2A | |
| SCHEMBL29965398 | 0.79 | CYP3A4 (0.46) | SMN1; SMN2HTTMAPTMEN1KMT2A | |
| SCHEMBL830793 | 0.79 | NCEH1 (0.59) | SMN1; SMN2HTTKMT2ANCEH1NPC1 | |
| SCHEMBL8694769 | 0.78 | HTR1D (0.62) | HTR1AHTR1DHTR1BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801553-A2 | PRODRUGS OF FULVESTRANT | Kashiv Biosciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |