Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBK | Q96KB5 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 10/20 | 0.43 |
| ▸ | ACACA | Q13085 | 6/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17501246 | 0.83 | DRD2 (0.45) | PBKDRD2ACACBACACAJAK2 | |
| SCHEMBL21789372 | 0.81 | JAK1 (0.45) | PBKDRD2JAK2JAK1 | |
| SCHEMBL28530478 | 0.81 | JAK1 (0.45) | PBKDRD2JAK2JAK1 | |
| SCHEMBL3816616 | 0.78 | KMT2A (0.56) | DRD2ACACBACACAKMT2ACKS1B | |
| SCHEMBL190838 | 0.78 | KMT2A (0.56) | DRD2ACACBACACAKMT2ACKS1B | |
| SCHEMBL3942686 | 0.78 | KMT2A (0.56) | DRD2ACACBACACAKMT2ACKS1B | |
| SCHEMBL4377073 | 0.78 | KMT2A (0.56) | DRD2ACACBACACAKMT2ACKS1B | |
| SCHEMBL17684700 | 0.78 | DRD2 (0.45) | PBKDRD2ACACBACACAJAK2 | |
| SCHEMBL17684701 | 0.78 | DRD2 (0.45) | PBKDRD2ACACBACACAJAK2 | |
| Bicarbonate SCHEMBL1580718 | 0.75 | KMT2A (0.57) | DRD2ACACBACACAKMT2ACKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240882-A1 | HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR USE IN TREATING ACUTE INFLAMMATION | TES PHARMA S.R.L. (IT) | 2024-11-28 | — | — | WO | disclosed |
| CN-118496217-A | Inhibitors of alpha-amino-beta-carboxyhexadienoic acid semialdehyde decarboxylase | TES制药有限责任公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-3883930-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | Tes Pharma S.r.l. (IT) | 2021-09-29 | — | — | EP | disclosed |