Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 3/20 | 0.32 |
| ▸ | CCR3 | P51677 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214467 | 0.82 | DDR1 (0.42) | DDR1P2RX7GAAAHRHSD17B10 | |
| SCHEMBL20304370 | 0.81 | PLK4 (0.42) | DDR1P2RX7GAAAHRHSD17B10 | |
| SCHEMBL30147962 | 0.81 | DDR1 (0.41) | DDR1P2RX7GAAAHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL29715665 | 0.81 | DDR1 (0.41) | DDR1P2RX7GAAAHRHSD17B10 | |
| SCHEMBL17057147 | 0.81 | DDR1 (0.41) | DDR1P2RX7GAAAHRHSD17B10 | |
| SCHEMBL29106671 | 0.77 | TSHR (0.57) | DDR1MAPK1P2RX7GAAAHR | |
| SCHEMBL353369 | 0.77 | DDR1 (0.47) | DDR1P2RX7GAAAHRHSD17B10 | |
| SCHEMBL29913411 | 0.74 | MEN1 (0.43) | DDR1GAAHSD17B10TSHRHRH1 | |
| Trifluoroacetic Acid SCHEMBL30591159 | 0.72 | MEN1 (0.55) | DDR1GAAHSD17B10TSHRALDH1A1 | |
| SCHEMBL30491310 | 0.72 | TSHR (0.37) | DDR1P2RX7GAAAHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3275868-B1 | PYRAZOLYLKETONE DERIVATES FOR USE AS INTERMEDIATES | AGC INC (JP) | 2021-09-29 | — | — | EP | disclosed |