Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 5/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 7/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23849891 | 0.83 | ACMSD (0.51) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL23849994 | 0.82 | ACMSD (0.61) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL23850126 | 0.76 | ACMSD (0.52) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL31313993 | 0.76 | ACMSD (0.70) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL23853749 | 0.76 | ACMSD (0.70) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL24088115 | 0.71 | PRNP (0.67) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL24087889 | 0.69 | PRNP (0.65) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL31053407 | 0.66 | PRNP (0.63) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL24087985 | 0.66 | RXFP1 (1.00) | PRNPRXFP1NPSR1KDM4EMAPT | |
| SCHEMBL26847398 | 0.66 | HPGD (0.64) | PRNPRXFP1NPSR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883930-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | Tes Pharma S.r.l. (IT) | 2021-09-29 | — | — | EP | disclosed |